All properties are independently selected. We may earn a commission from bookings, but this does not affect our recommendations.

Affiliate disclosure

All properties are independently selected. We may earn a commission from bookings, but this does not affect our recommendations.

Hotel Florence
All articles
Top Hotels in Santo Spirito Florence for Every Traveler

The Florence Journal

Top Hotels in Santo Spirito Florence for Every Traveler

Your comprehensive guide to the best Santo Spirito hotels for unforgettable stays in Florence.

Mateo
by Mateo Rodriguez
Verified Expert
Updated Apr 1, 2026
7 min read
242 visits
Top Hotels in Santo Spirito Florence for Every Traveler

Top Hotels Santo Spirito Florence On Map

All hotels were sorted by rating and number of reviews

Hotels featured in this article
1. Hotel Lungarno - Lungarno Collection
2. B&B Hotel Firenze Pitti Palace Al Ponte Vecchio
3. Hotel Torre Di Bellosguardo
4. BSJ15-Borgo San Jacopo Room
5. 7Heaven Pontevecchio Rooms
6. Una Hotels Vittoria Firenze
7. Althea Rooms
8. Hotel Palazzo Guadagni
9. Soprarno Suites
10. Palazzo Ridolfi - Residenza D'Epoca
11. Hotel La Scaletta Al Ponte Vecchio
12. Mia Palace
13. Palazzo Guicciardini
14. Piazza Pitti Palace - Residenza D'Epoca
15. Palazzo Mannaioni Suites

We curated a selection of hotels in Santo Spirito, Florence based on their location, unique design, and traveler reviews. Each option balances historical charm with modern amenities, ensuring a fulfilling stay.

This neighborhood is known for its vibrant artisan community, bustling market squares, and storied streets. Famous nearby attractions include the Pitti Palace and Boboli Gardens, just minutes away from our recommended spots.

Why Stay in Santo Spirito?

Santo Spirito is ideal for travelers seeking an authentic Florentine experience. It boasts trendy cafes like Caffè Ricci, art galleries, and boutiques, appealing to young professionals and families alike. Notable hotels such as Palazzo Guichard and Hotel Villa la Palagina rank highly among guests.

The area is only 1.5 km from Florence's historic center, making it easily accessible via bus lines and a 10-minute walk to major attractions. Santo Spirito also features local markets and artisanal shops, enhancing its charm and making it a great base for exploring Florence.

Is Santo Spirito Safe?

Santo Spirito is generally considered safe and welcoming to visitors. With a consistent police presence and frequent foot traffic, tourists usually feel secure. For after-dark travel, streets like Via della Pergola offer well-lit paths. However, it's wise to stay vigilant against pickpocketing, especially near crowded spots like the Santo Spirito square.

Luxury Accommodations in Santo Spirito, Florence

  • 652 m from center
    -
    Hotel Lungarno - Lungarno Collection Hotel Lungarno - Lungarno Collection Hotel Lungarno - Lungarno Collection Hotel Lungarno - Lungarno Collection Hotel Lungarno - Lungarno Collection

    That was just a preview — check out all hotel photos.

    Best by gourmet dining
    1/1

    MAIN FEATURES

    • Michelin-starred dining with exceptional reviews for Italian cuisine
    • Exquisite rooms adorned with artworks by renowned artists, including Picasso
    • Exclusive access to the Salvatore Ferragamo Museum for style enthusiasts
    Set on the banks of the Arno River, Hotel Lungarno offers exquisite decor with original modern art. This luxury haven features Michelin-starred dining and stunning terrace views. Just steps away from the famed Ponte Vecchio, guests can easily visit Florence's highlights. The historic ambiance, rich culture, and unique amenities ensure an unforgettable stay.

    Rooms filling fast – secure the best rate! 

    €743-€1005 per night

    Rates from verified hotel providers

  • 656 m from center
    -
    B&B Hotel Firenze Pitti Palace Al Ponte Vecchio B&B Hotel Firenze Pitti Palace Al Ponte Vecchio B&B Hotel Firenze Pitti Palace Al Ponte Vecchio B&B Hotel Firenze Pitti Palace Al Ponte Vecchio B&B Hotel Firenze Pitti Palace Al Ponte Vecchio

    That was just a preview — check out all hotel photos.

    Best by rooftop views
    1/1

    MAIN FEATURES

    • Panoramic terrace dining with local cuisine showcasing Tuscan flavors
    • Strategically located steps from iconic attractions like the Uffizi Gallery
    • Pet-friendly policies for animal lovers visiting the city
    Situated in the historic Rossi Tower, this charming hotel features a rooftop terrace restaurant with breathtaking views of Florence. Just steps from Ponte Vecchio and the Uffizi Gallery, it offers local Tuscan cuisine in a cozy setting. Experience authentic hospitality near Florence's most illustrious landmarks in this elegantly appointed space.
    €94-€204 per night

    Rates from verified hotel providers

  • 3. Hotel Torre Di Bellosguardo

    8.3 Very Good
    179 reviews
    2 km from center
    -
    Hotel Torre Di Bellosguardo Hotel Torre Di Bellosguardo Hotel Torre Di Bellosguardo Hotel Torre Di Bellosguardo Hotel Torre Di Bellosguardo

    That was just a preview — check out all hotel photos.

    Best for family-friendly offerings
    1/1

    MAIN FEATURES

    • Cooking classes led by local chefs to immerse in Tuscan culinary traditions
    • Captivating views over Florence's skyline from serene gardens
    • A small capacity offers personalized hospitality and unique experiences
    Perched above the city, Hotel Torre Di Bellosguardo boasts gardens and tranquil settings, with family-friendly amenities that delight. Guests enjoy seasonal cooking classes and fresh produce from the organic garden. Located a short drive from the city center, this historical gem provides an intimate escape while remaining close to Florence's rich culture.

    Hurry – almost gone at this price! 

    €310-€516 per night

    Rates from verified hotel providers

  • 4. BSJ15-Borgo San Jacopo Room

    9.3 Superb
    548 reviews
    658 m from center
    -
    BSJ15-Borgo San Jacopo Room BSJ15-Borgo San Jacopo Room BSJ15-Borgo San Jacopo Room BSJ15-Borgo San Jacopo Room BSJ15-Borgo San Jacopo Room

    That was just a preview — check out all hotel photos.

    Best for cultural immersion
    1/1

    MAIN FEATURES

    • Personalized breakfast options tailored to local Italian specialties
    • Family rooms designed for convenience with group travels in mind
    • Concierge services available for authentic local experiences and tours
    Located steps from Ponte Vecchio, BSJ15-Borgo San Jacopo Room showcases modern decor and is perfect for travelers seeking proximity to Florence's cultural sites. Each room is designed with comfort in mind, featuring stylish amenities. Your adventure begins at this delightful guesthouse, making it easy to visit landmarks like the Uffizi Gallery and Piazza della Signoria.

    Rooms filling fast – secure the best rate! 

    €214-€195 per night

    Rates from verified hotel providers

  • 5. 7Heaven Pontevecchio Rooms

    7.8 Good
    498 reviews
    658 m from center
    -
    7Heaven Pontevecchio Rooms 7Heaven Pontevecchio Rooms 7Heaven Pontevecchio Rooms 7Heaven Pontevecchio Rooms 7Heaven Pontevecchio Rooms

    That was just a preview — check out all hotel photos.

    Best for romantic stays
    1/1

    MAIN FEATURES

    • Boutique-style rooms equipped with hot tubs for a luxurious touch
    • Location with a high score of 9.5 for centrality in Florence
    • Just 11 km from Florence Airport, ensuring easy access for travel
    Charming and inviting, 7Heaven Pontevecchio Rooms combines style with convenience. Its boutique touches and hot tub options make it a romantic getaway, just a short stroll from the Ponte Vecchio. Modern amenities enhance the stay while maintaining close access to cultural landmarks, ensuring a perfect balance of relaxation and exploration in Florence.
    €81-€256 per night

    Rates from verified hotel providers

Central Hotels in Santo Spirito, Florence

  • 6. Una Hotels Vittoria Firenze

    8.3 Very Good
    1362 reviews
    2 km from center
    -
    Una Hotels Vittoria Firenze Una Hotels Vittoria Firenze Una Hotels Vittoria Firenze Una Hotels Vittoria Firenze Una Hotels Vittoria Firenze

    That was just a preview — check out all hotel photos.

    Best by design aesthetics
    1/1

    MAIN FEATURES

    • On-site restaurant serving a seasonal menu of local Tuscan ingredients
    • Complimentary bicycle rentals for exploring Florence at your pace
    • Stunning outdoor garden bar ideal for relaxation and social gatherings
    Located in the historic San Frediano quarter, UNA Hotels Vittoria Firenze presents a stunning fusion of modern design and traditional Florentine hospitality. With uniquely styled rooms filled with mosaics and bright hues, the hotel crafts a memorable stay. Guests are moments away from cultural highlights such as the Uffizi Gallery and Boboli Gardens.

    Hurry – almost gone at this price! 

    €152-€357 per night

    Rates from verified hotel providers

  • 7. Althea Rooms

    9.1 Superb
    774 reviews
    1 km from center
    -
    Althea Rooms Althea Rooms Althea Rooms Althea Rooms Althea Rooms

    That was just a preview — check out all hotel photos.

    Best for personalized service
    1/1

    MAIN FEATURES

    • Personalized restaurant recommendations from welcoming owners
    • Daily housekeeping to ensure a tidy and comfortable environment
    • Smoke-free hotel atmosphere appealing to health-conscious travelers
    Nestled on the quaint side of the Arno, Althea Rooms charms guests with personalized service and excellent recommendations for local dining. This smoke-free environment offers comfort with modern amenities and warm hospitality. Located steps from the Boboli Gardens and Ponte Vecchio, it's an ideal launchpad for cultural explorations.

    Just a few rooms left at the best rate! 

    €28-€97 per night

    Rates from verified hotel providers

  • 8. Hotel Palazzo Guadagni

    9.1 Superb
    333 reviews
    965 m from center
    -
    Hotel Palazzo Guadagni Hotel Palazzo Guadagni Hotel Palazzo Guadagni Hotel Palazzo Guadagni Hotel Palazzo Guadagni

    That was just a preview — check out all hotel photos.

    Best for historic ambiance
    1/1

    MAIN FEATURES

    • Roof garden bar offering breathtaking views of Florence's skyline
    • Cozy ambiance enhanced by antique furniture and historical details
    • Pet-friendly policies accommodating travelers with furry companions
    Hotel Palazzo Guadagni, housed in a stunning 16th-century palace, showcases history with its antique decor and frescoes. Relax on the rooftop terrace with panoramic views of Florence. This boutique escape is in the heart of the Oltrarno neighborhood, a short walk from key attractions like Boboli Gardens and the iconic Ponte Vecchio.

    Rooms filling fast – secure the best rate! 

    €347-€496 per night

    Rates from verified hotel providers

  • 9. Soprarno Suites

    9.3 Superb
    348 reviews
    949 m from center
    -
    Soprarno Suites Soprarno Suites Soprarno Suites Soprarno Suites Soprarno Suites

    That was just a preview — check out all hotel photos.

    Best for unique charm
    1/1

    MAIN FEATURES

    • Individually decorated rooms with personalized art and crafts
    • Access to communal spaces fostering a community-focused environment
    • Diverse breakfast options prominently featuring local delicacies
    Soprarno Suites, a chic boutique hotel, offers a serene escape in Florence's lively Oltrarno district. Each room features unique artistic themes tailored to local culture, providing a thoughtful touch. Conveniently located near landmarks like the Ponte Vecchio, it combines elegance with authenticity that enriches your Florence stay.
    €108-€243 per night

    Rates from verified hotel providers

  • 832 m from center
    -
    Palazzo Ridolfi - Residenza D'Epoca Palazzo Ridolfi - Residenza D'Epoca Palazzo Ridolfi - Residenza D'Epoca Palazzo Ridolfi - Residenza D'Epoca Palazzo Ridolfi - Residenza D'Epoca

    That was just a preview — check out all hotel photos.

    Best for luxury and history
    1/1

    MAIN FEATURES

    • Luxurious suites blending antique architecture with modern conveniences
    • In-room massage services available for relaxation after a day of sightseeing
    • Exceptional breakfast featuring authentic local cuisine options
    Palazzo Ridolfi, steeped in Renaissance history, offers luxurious accommodations through spacious suites adorned with antiques. This centrally located hotel in Florence provides easy access to culinary experiences and artisan shops. Its warm, personalized service creates a tranquil retreat amidst the bustling city, perfect for both families and cultural enthusiasts.
    €223-€389 per night

    Rates from verified hotel providers

Airport Hotels in Santo Spirito, Florence

  • 758 m from center
    -
    Hotel La Scaletta Al Ponte Vecchio Hotel La Scaletta Al Ponte Vecchio Hotel La Scaletta Al Ponte Vecchio Hotel La Scaletta Al Ponte Vecchio Hotel La Scaletta Al Ponte Vecchio

    That was just a preview — check out all hotel photos.

    Best by historical charm
    1/1

    MAIN FEATURES

    • Rooftop terrace dining highlighting local Tuscan cuisine with stunning views
    • Personalized guest experiences crafted for couples and cultural enthusiasts
    • Proximity to must-see attractions like Palazzo Pitti and historic landmarks
    Set within a captivating 15th-century structure, Hotel La Scaletta offers an enchanting retreat close to Florence's cultural treasures. The rooftop terrace provides panoramic views of the Arno and the Ponte Vecchio. Luxurious jacuzzi rooms invite romance, while the artisan-rich Oltrarno district adds a unique flair to your stay, just moments from the Uffizi Gallery.
    €873-€1216 per night

    Rates from verified hotel providers

  • 12. Mia Palace

    8.2 Very Good
    959 reviews
    1 km from center
    -
    Mia Palace Mia Palace Mia Palace Mia Palace Mia Palace

    That was just a preview — check out all hotel photos.

    Best for budget travelers
    1/1

    MAIN FEATURES

    • Spacious attic rooms designed with historical ambiance and modern comforts
    • Complimentary buffet breakfast featuring seasonal, local offerings
    • Shared kitchen facilities that allow for a home-like feel during stays
    Mia Palace combines comfort and affordability in a charming setting close to Florence's heart. Offering spacious attic rooms with unique historical elements, it's a great choice for families and business travelers alike. Located near the historic center, visitors can effortlessly access attractions like Ponte Vecchio and Santa Maria Novella station.
    €67-€161 per night

    Rates from verified hotel providers

  • 13. Palazzo Guicciardini

    8.8 Fabulous
    775 reviews
    729 m from center
    -
    Palazzo Guicciardini Palazzo Guicciardini Palazzo Guicciardini Palazzo Guicciardini Palazzo Guicciardini

    That was just a preview — check out all hotel photos.

    Best for personalized service
    1/1

    MAIN FEATURES

    • Complimentary access to 72 museums with the unique Firenze Card
    • Bespoke fragrance experiences crafted by a professional perfumer
    • Cozy ambiance set within a historical building with original artwork
    A boutique experience awaits at Palazzo Guicciardini, where Renaissance decor meets modern amenities. Nestled in the Oltrarno district, this historic hotel offers a charm that captivates all who enter. Enjoy the complimentary Firenze Card for museum entries, alongside a unique fragrance creation experience - perfect for couples seeking a romantic adventure in Florence.

    Just a few rooms left at the best rate! 

    €386-€198 per night

    Rates from verified hotel providers

  • 967 m from center
    -
    Piazza Pitti Palace - Residenza D'Epoca Piazza Pitti Palace - Residenza D'Epoca Piazza Pitti Palace - Residenza D'Epoca Piazza Pitti Palace - Residenza D'Epoca Piazza Pitti Palace - Residenza D'Epoca

    That was just a preview — check out all hotel photos.

    Best for historical ambiance
    1/1

    MAIN FEATURES

    • A remarkable ambiance accented by Renaissance art throughout the hotel
    • Jacuzzi suite options available for an indulgent experience
    • Exceptional service focusing on personalized guest needs and comfort
    Situated just steps from Pitti Palace, this evocative hotel delivers an exceptional stay steeped in history. Piazza Pitti Palace showcases elegant decor inspired by the Renaissance. Each room offers modern comforts, including Jacuzzis in select suites. The intimate atmosphere combined with proximity to cultural landmarks like Ponte Vecchio creates an unforgettable setting.

    Just a few rooms left at the best rate! 

    €348-€513 per night

    Rates from verified hotel providers

  • 15. Palazzo Mannaioni Suites

    9.1 Superb
    538 reviews
    800 m from center
    -
    Palazzo Mannaioni Suites Palazzo Mannaioni Suites Palazzo Mannaioni Suites Palazzo Mannaioni Suites Palazzo Mannaioni Suites

    That was just a preview — check out all hotel photos.

    Best for spacious accommodations
    1/1

    MAIN FEATURES

    • Spacious apartments designed with historical charm and modern amenities
    • Fully equipped kitchenettes perfect for self-catering during stays
    • Quiet location offering proximity to local dining and cultural spots
    Palazzo Mannaioni Suites presents an elegant array of spacious apartments within an enchanting 15th-century building. Ideal for families and leisure travelers, guests can revel in the comforts of fully-equipped kitchen facilities. Located in the serene Oltrarno district, it offers easy access to Florence's major attractions for an authentic local experience.

    Hurry – almost gone at this price! 

    €135-€251 per night

    Rates from verified hotel providers

Final Thoughts

Staying at one of the best hotels in Santo Spirito ensures a central location with easy access to Florence's iconic landmarks. Within walking distance, guests can explore the Uffizi Gallery, Boboli Gardens, and the historic Ponte Vecchio. This vibrant district offers an authentic taste of local culture, enhanced by various dining options and artisan shops just around the corner. These hotels provide convenience and comfortable access to essential transport lines for easy exploration of the city.

The curated selection of hotels in Santo Spirito offers unique amenities such as rooftop terraces, jacuzzis in select rooms, and personalized guest experiences. Whether you seek luxury or budget-friendly options, each property incorporates local charm and character. Choosing the best hotels in this lively area guarantees an enriching stay amid Florence's artistic heritage. Take the next step and secure your accommodation today.

Was this article helpful to you? Thanks for your feedback
7 min read
  • Why Stay in Santo Spirito?
  • Is Santo Spirito Safe?
  • Luxury Accommodations in Santo Spirito, Florence

    • 1. Hotel Lungarno - Lungarno Collection
    • 2. B&B Hotel Firenze Pitti Palace Al Ponte Vecchio
    • 3. Hotel Torre Di Bellosguardo
    • 4. BSJ15-Borgo San Jacopo Room
    • 5. 7Heaven Pontevecchio Rooms
  • Central Hotels in Santo Spirito, Florence

    • 6. Una Hotels Vittoria Firenze
    • 7. Althea Rooms
    • 8. Hotel Palazzo Guadagni
    • 9. Soprarno Suites
    • 10. Palazzo Ridolfi - Residenza D'Epoca
  • Airport Hotels in Santo Spirito, Florence

    • 11. Hotel La Scaletta Al Ponte Vecchio
    • 12. Mia Palace
    • 13. Palazzo Guicciardini
    • 14. Piazza Pitti Palace - Residenza D'Epoca
    • 15. Palazzo Mannaioni Suites
  • Final Thoughts

You may also like

Explore more articles with curated hotel picks and local insights you might enjoy

Best Hotels Near Uffizi in Florence

Best Hotels Near Uffizi in Florence

Rodriguez
by Mateo Rodriguez
Verified Expert
Updated Apr 1, 2026 8 min read
Gems of Uffizi, Florence await-handpicked stays from exquisite boutique hotels to lavish residences, revealing hidden artistic treasures.
Best Hotels in Florence Historic Centre for All Types

Best Hotels in Florence Historic Centre for All Types

Rodriguez
by Mateo Rodriguez
Verified Expert
Updated Apr 1, 2026 5 min read
Gems in Florence Historic Centre range from luxury escapes to boutique gems that offer stunning views over the lively piazzas.

Do you want to know more about Florence?

Show all articles
100% Verified Reviews
Select language
Currency
  • USD U.S. dollar
  • EUR Euro
  • GBP Pound sterling
  • AUD Australian dollar
  • CAD Canadian dollar
  • BRL Brazilian real
  • BGN Bulgarian lev
  • CNY Chinese yuan
  • CZK Czech koruna
  • DKK Danish krone
  • HKD Hong Kong dollar
  • ILS Israeli new sheqel
  • JPY Japanese yen
  • MYR Malaysian ringgit
  • NZD New Zealand dollar
  • NOK Norwegian krone
  • PLN Polish zloty
  • RON Romanian leu
  • RUB Russian ruble
  • SAR Saudi riyal
  • SGD Singapore dollar
  • ZAR South African rand
  • KRW South Korean won
  • SEK Swedish krona
  • CHF Swiss franc
  • TRY Turkish lira
  • UAH Ukrainian hryvnia
  • THB Thai baht
  • ARS Argentina, Peso
Contact Us
hotel Florence
Your details
Subject:
Message:
Your message has been sent
Your message was not delivered